Complex Conditions & Polygenic Risk Scores: Direct-to-Consumer Genetic Testing

Learn about the contribution of genetics and lifestyle to complex and polygenic conditions.

Complex conditions have many contributing factors including genetics and lifestyle, and polygenic conditions have a cause influenced by mutliple genetic factors. Understanding family and twin studies, GWAS, heritability, genetic liability or load, and statistical methods like polygenic risk score (PGS or PRS) are covered in this thorough discussion of complex factors that influence risk for disease.