Explore 23andMe genetic reports.
Take some time to download the report examples that interest you to better understand the types of information your patients receive and may wish to share with you.
Take some time to download the report examples that interest you to better understand the types of information your patients receive and may wish to share with you.
The Health Predispositions category includes both reports that meet FDA requirements for Genetic Health Risks and reports Powered by 23andMe Research. These reports are not intended to tell a person anything about his or her current state of health, or to be used to make medical decisions.
Those with a personal or family history of any of these conditions should speak with their healthcare provider to determine if comprehensive genetic testing is appropriate.
Each Genetic Health Risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. These reports are not intended to tell a person anything about his or her current state of health, or to be used to make medical decisions, including whether or not he or she should take a medication or how much of a medication should be taken.
|Report||Gene||Variants||Best Studied Ethnicities|
Age-Related Macular Degeneration
||GeneCFH, ARMS2||Variants2||Relevant Ethnicities All ethnicities but best studied in Europeans|
Alpha-1 Antitrypsin Deficiency
||GeneSERPINA1||Variants2||Relevant Ethnicities European|
BRCA1/BRCA2 (Selected Variants)
||GeneBRCA1, BRCA2||Variants3||Relevant Ethnicities Ashkenazi Jewish|
||GeneHLA-DQA1, HLA-DQB1||Variants2||Relevant Ethnicities All ethnicities but best studied in Europeans|
|Report Chronic Kidney Disease (APOL1-Related)||GeneAPOL1||Variants2||Relevant Ethnicities African/African American|
|Report Familial Hypercholesterolemia||GeneLDLR, APOB||Variants24||Relevant Ethnicities European, Lebanese, Old Order Amish|
|Report G6PD Deficiency||GeneG6PD||Variants2||Relevant Ethnicities African, Southern European, Kurdish Jewish, Middle Eastern, Central Asian, South Asian descent|
|Report Hereditary Amyloidosis (TTR-Related)||GeneTTR||Variants3||Relevant Ethnicities African American, West African, Portuguese, Japanese, Northern Swedish, Irish, British|
Hereditary Hemochromatosis (HFE-Related)
||GeneHFE||Variants2||Relevant Ethnicities Europeans|
||GeneF2, F5||Variants2||Relevant Ethnicities European|
|Report Late-Onset Alzheimer’s Disease||GeneAPOE||Variants1||Relevant Ethnicities European|
|Report MUTYH-Associated Polyposis||GeneMUTYH||Variants2||Relevant Ethnicities Northern European|
||GeneLRRK2, GBA||Variants2||Relevant Ethnicities European, Ashkenazi Jewish, North African Berber|
Reports that are “Powered by 23andMe Research” are developed using data and insights gathered from thousands of customers who consented to participate in our research.
|POLYGENIC REPORTS||VARIANTS CONTRIBUTING TO MODEL||RELEVANT ETHNICITIES|
|Report Atrial Fibrillation||Variants2000+||Relevant Ethnicities European, Hispanic/Latino, East/Southeast Asian, South Asian, Sub-Saharan African/African American, Northern African/Central and Western Asian descent|
|Report Coronary Artery Disease||Variants2000+||Relevant Ethnicities European, Hispanic/Latino, East/Southeast Asian, South Asian, Sub-Saharan African/African American, Northern African/Central and Western Asian descent|
|Report Gout||Variants21,000+||Relevant Ethnicities European, Hispanic/Latino, East/Southeast Asian, South Asian, Sub-Saharan African/African American, Northern African/Central and Western Asian descent|
|Report High Blood Pressure||Variants2000+|
|Report LDL Cholesterol||Variants2000+|
|Report Nonalcoholic Fatty Liver Disease||Variants1400+|
|Report Obstructive Sleep Apnea||Variants23,000+|
|Report Restless Legs Syndrome||Variants23,000+|
|Report Type 2 Diabetes||Variants1000+||Relevant Ethnicities European, Hispanic/Latino, African, East Asian, South Asian|
|Report Uterine Fibroids||Variants1000+|
These reports include specific variants that can impact the body’s ability to process certain medications. These reports only include a subset of possible variants involved in medication processing and they are not intended to provide information on association between specific DNA variants and any specific medications. Results should not be used to make medical decisions.
CYP2C19 Drug Metabolism
||GeneCYP2C19||Variants3||Relevant Ethnicities The DNA variants included in this test are found in many ethnicities. See Scientific Details for more information.|
DPYD Drug Metabolism
||GeneDPYD||Variants2||Relevant Ethnicities The DNA variants included in this test are found in many ethnicities. See Scientific Details for more information.|
|Report SLCO1B1 Drug Transport||GeneSLCO1B1||Variants1||Relevant Ethnicities The DNA variants included in this test are found in many ethnicities. See Scientific Details for more information.|
These reports include genetic variants that have been linked to recessive conditions and provide insight into carrier status for the conditions listed below. These reports include only a subset of possible variants that may be linked to a condition, and it is possible to have other variants not included in these reports. Those with a family history of any of these conditions or increased risk based on ethnicity or family origin and are considering having children should discuss options for comprehensive testing with their healthcare provider.
Note: Sample reports do not cover all possible test result outcomes, and for many reports, residual risk estimates vary by ethnicity.
|Report Agenesis of the Corpus Callosum with Peripheral Neuropathy||GeneSLC12A6||Variants1||Relevant Ethnicities French Canadian|
|Report ARSACS||GeneSACS||Variants1||Relevant Ethnicities French Canadian|
|Report Autosomal Recessive Polycystic Kidney Disease||GenePKHD1||Variants3||Relevant Ethnicities Not applicable|
|Report Beta Thalassemia and Related Hemoglobinopathies||GeneHBB||Variants10||Relevant Ethnicities Cypriot, Greek, Italian, Sicilian, Sardinian|
|Report Bloom Syndrome||GeneBLM||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Canavan Disease||GeneASPA||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Congenital Disorder of Glycosylation Type 1a (PMM2-CDG)||GenePMM2||Variants2||Relevant Ethnicities Danish|
|Report Cystic Fibrosis||GeneCFTR||Variants29||Relevant Ethnicities European, Hispanic/Latino, Ashkenazi Jewish|
|Report D-Bifunctional Protein Deficiency||GeneHSD17B4||Variants2||Relevant Ethnicities Not applicable|
|Report Dihydrolipoamide Dehydrogenase Deficiency||GeneDLD||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Familial Dysautonomia||GeneIKBKAP||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Familial Hyperinsulinism (ABCC8-Related)||GeneABCC8||Variants3||Relevant Ethnicities Ashkenazi Jewish|
|Report Familial Mediterranean Fever||GeneMEFV||Variants7||Relevant Ethnicities Arab, Armenian, Sephardic Jewish, Turkish|
|Report Fanconi Anemia Group C||GeneFANCC||Variants3||Relevant Ethnicities Ashkenazi Jewish|
|Report Gaucher Disease Type 1||GeneGBA||Variants3||Relevant Ethnicities Ashkenazi Jewish|
|Report Glycogen Storage Disease Type Ia||GeneG6PC||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Glycogen Storage Disease Type Ib||GeneSLC37A4||Variants2||Relevant Ethnicities Not applicable|
|Report GRACILE Syndrome||GeneBCS1L||Variants1||Relevant Ethnicities Finnish|
|Report Hereditary Fructose Intolerance||GeneALDOB||Variants4||Relevant Ethnicities European|
|Report Herlitz Junctional Epidermolysis Bullosa (LAMB3-Related)||GeneLAMB3||Variants3||Relevant Ethnicities Not applicable|
|Report Leigh Syndrome, French Canadian Type||GeneLRPPRC||Variants1||Relevant Ethnicities French Canadian|
|Report Limb-Girdle Muscular Dystrophy Type 2D||GeneSGCA||Variants1||Relevant Ethnicities Finnish|
|Report Limb-Girdle Muscular Dystrophy Type 2E||GeneSGCB||Variants1||Relevant Ethnicities Southern Indiana Amish|
|Report Limb-Girdle Muscular Dystrophy Type 2I||GeneFKRP||Variants1||Relevant Ethnicities European|
|Report Maple Syrup Urine Disease Type 1B||GeneBCKDHB||Variants2||Relevant Ethnicities Ashkenazi Jewish|
|Report MCAD Deficiency||GeneACADM||Variants4||Relevant Ethnicities Northern European|
|Report Mucolipidosis Type IV||GeneMCOLN1||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Neuronal Ceroid Lipofuscinosis (CLN5-Related)||GeneCLN5||Variants1||Relevant Ethnicities Finnish|
|Report Neuronal Ceroid Lipofuscinosis (PPT1-Related)||GenePPT1||Variants3||Relevant Ethnicities Finnish|
|Report Niemann-Pick Disease Type A||GeneSMPD1||Variants3||Relevant Ethnicities Ashkenazi Jewish|
|Report Nijmegen Breakage Syndrome||GeneNBN||Variants1||Relevant Ethnicities Eastern European|
|Report Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related)||GeneGJB2||Variants2||Relevant Ethnicities Ashkenazi Jewish, European|
|Report Pendred Syndrome and DFNB4 Hearing Loss||GeneSLC26A4||Variants6||Relevant Ethnicities Not applicable|
|Report Phenylketonuria and Related Disorders||GenePAH||Variants23||Relevant Ethnicities Northern European|
|Report Primary Hyperoxaluria Type 2||GeneGRHPR||Variants1||Relevant Ethnicities European|
|Report Rhizomelic Chondrodysplasia Punctata Type 1||GenePEX7||Variants1||Relevant Ethnicities Not applicable|
|Report Salla Disease||GeneSLC17A5||Variants1||Relevant Ethnicities Finnish, Swedish|
|Report Sickle Cell Anemia||GeneHBB||Variants1||Relevant Ethnicities African|
|Report Sjögren-Larsson Syndrome||GeneALDH3A2||Variants1||Relevant Ethnicities Swedish|
|Report Tay-Sachs Disease||GeneHEXA||Variants4||Relevant Ethnicities Ashkenazi Jewish, Cajun|
|Report Tyrosinemia Type I||GeneFAH||Variants4||Relevant Ethnicities French Canadian, Finnish|
|Report Usher Syndrome Type 1F||GenePCDH15||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Usher Syndrome Type 3A||GeneCLRN1||Variants1||Relevant Ethnicities Ashkenazi Jewish|
|Report Zellweger Syndrome Spectrum (PEX1-Related)||GenePEX1||Variants1||Relevant Ethnicities Not applicable|
These reports describe how genetics influence traits and conditions related to lifestyle and environment.
|Report Alcohol Flush Reaction||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Caffeine Consumption||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Deep Sleep||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Genetic Weight||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Lactose Intolerance||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Muscle Composition||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Saturated Fat and Weight||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Sleep Movement||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
These reports help consumers learn about their origins and ancient ancestors based on their DNA.
|Report Ancestry Composition||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Maternal Haplogroup||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Neanderthal Ancestry||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Paternal Haplogroup||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Your DNA Family||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
These reports are a fun way for consumers to learn about how genetics influence traits like eye color, hair texture and taste preference.
|Report Ability to Match Musical Pitch||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Asparagus Odor Detection||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Back Hair (available for men only)||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Bald Spot (available for men only)||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Bitter Taste||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Cheek Dimples||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Cilantro Taste Aversion||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Cleft Chin||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Dandruff||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Earlobe Type||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Early Hair Loss (available for men only)||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Earwax Type||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Eye Color||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Fear of Heights||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Finger Length Ratio||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Freckles||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Hair Photobleaching (hair lightening from the sun)||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Hair Texture||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Hair Thickness||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Ice Cream Flavor Preference||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Light or Dark Hair||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Misophonia||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Mosquito Bite Frequency||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Newborn Hair||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Photic Sneeze Reflex||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Red Hair||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Skin Pigmentation||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Stretch Marks||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Sweet vs. Salty||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Toe Length Ratio||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Unibrow||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Wake-Up Time||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
|Report Widow’s Peak||GeneNot applicable||VariantsNot applicable||Relevant Ethnicities|
Our customers have access to their raw genetic data, which they can view or download from their 23andMe account. This data has undergone a general quality review; however, only a subset of markers have been individually validated for accuracy. As such, the data from 23andMe’s Browse Raw Data feature is suitable only for research and educational and informational use and not for medical, diagnostic or other use.
The raw data could include sensitive information. Within the data, your patients could discover sensitive information about themselves and family members with whom they share their DNA. For example, comparing data between family members could reveal misattributed paternity.
*The 23andMe PGS test includes health predisposition and carrier status reports. Health predisposition reports include both reports that meet US FDA requirements for genetic health risks and the 23andMe Type 2 Diabetes health predisposition report which is based on 23andMe research and has not been reviewed by the FDA. The test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks and reporting carrier status. It is not intended to diagnose any disease. Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. The test is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatment. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future, the health of your fetus, or your newborn child’s risk of developing a particular disease later in life. For certain conditions, we provide a single report that includes information on both carrier status and genetic health risk. Warnings & Limitations: The 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of the 185delAG and 5382insC variants in the BRCA1 gene and the 6174delT variant in the BRCA2 gene. The report describes if a woman is at increased risk of developing breast and ovarian cancer, and if a man is at increased risk of developing breast cancer or may be at increased risk of developing prostate cancer. The three variants included in this report are most common in people of Ashkenazi Jewish descent and do not represent the majority of BRCA1/BRCA2 variants in the general population. The MUTYH-Associated Polyposis Genetic Health Risk Report is indicated for reporting the Y179C and G396D variants in the MUTYH gene and an increased risk for colorectal cancer. The two variants included in this report are most common in people of Northern European descent. These reports do not include variants in other genes linked to hereditary cancers and the absence of variants included in these reports do not rule out the presence of other genetic variants that may impact cancer risk. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed in a clinical setting before taking any medical action. For important information and limitations regarding other genetic health risk reports and carrier status reports, visit 23andme.com/test-info.
The 23andMe PGS test uses qualitative genotyping to detect 6 variants in 3 genes in the genomic DNA of adults from saliva for the purpose of reporting and interpreting information about the processing of certain therapeutics to inform discussions with a healthcare professional. It does not describe if a person will or will not respond to a particular therapeutic and does not describe the association between detected variants and any specific therapeutic. Results should be confirmed in a clinical setting with independent genetic testing before taking any medical action. Warning: Test information should not be used to start, stop, or change any course of treatment and does not test for all possible variants that may affect metabolism or protein function. The PGS test is not a substitute for visits to a healthcare professional. Making changes to your current regimen can lead to harmful side effects or reduced intended benefits of your medication, therefore consult with your healthcare professional before taking any medical action. For a complete list of the 6 variants tested, visit https://permalinks.23andme.com/pdf/pgt_product_info_page_21jan2020.pdf.